This Guidance Note explores the relevance of insider mediation in 21^st century practice-policy landscape, seeks to foster an understanding of the theoretical and practical underpinnings of the 'insider mediation' concept and provide practical knowledge and a step-by-step guide to engaging with insider mediators. Case studies are used throughout the Guidance Note to highlight how insider mediators work on a wide range of thematic issues, including peace processes, natural resource-related conflicts, electoral-related violence, building social cohesion and addressing religious and faith-related issues.